GiveWell is a nonprofit dedicated to identifying outstanding giving opportunities and publishing the full details of its analyses to help donors decide where to give. They focus not just on financials, such as evaluating administrative and fundraising costs, but instead conduct in-depth research to determine how much good per dollar a specific program accomplishes (in terms of lives saved, lives improved, etc.).
GiveWell Inu ($GINU) was created in response to Vitalik Buterins latest tweet.